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Online Hizmetlere Toplu BakışSouthern Clinics Of Istanbul Eurasia
South Clin Ist Euras. 2003; 14(2): 74-80 | |||
Düzenli Hemodiyaliz Tedavisi Gören Kronik Renal Yetmezlikli Olgularda Hemostatik Parametrelerdeki DeğişmelerIşık Türkalp1, Aliye Karabulut2, Didem Özkazanç31Diamed Diyaliz Merkezi2Tekirdağ Devlet Hastanesi 3Haydarpaşa Numune Hastanesi AMAÇ: Alterations In Haemostatic Parameters In Patients With Chronic Renal Failure On Regular Hemodialysis TreatmentIşık Türkalp1, Aliye Karabulut2, Didem Özkazanç31Diamed Diyaliz Merkezi2Tekirdağ Devlet Hastanesi 3Haydarpaşa Numune Hastanesi OBJECTIVE: In order to investigate the changes of haemostatic parameters and the effects of regular hemodialysis in the patients with chronic renal failure (CRF) we studied in 20 healthy controls and in 20 patients with CRF undergoing regular hemodialysis with cuprophan (CP) membrane. To show the effects of hemodialysis we investigated blood samples of working group before and after hemodialysis. In all groups we determined AT III, D-dimer, platelets, fibrinogen, FDP, PT, PTT and routine parameters. In working group before dialysis platelets were lower than controls and fibrinogen levels were higher and AT III levels were lower and D-dimer levels were higher and PT was longer, PTT was found in the normal ranges in each group. There were no established differences between haemostatic parameters before and after dialysis. Decrease of AT III activity and increase of fibrinogen concentration in the patients with CRF undergoing regular hemodialysis treatment that we established in this study showed the developing of hypercoagulation in this cases, and increase of FDP-D-dimer concentrations showed the activation of fibrinolytic system secondary of hypercoagulation. Because of AT III and D-dimer don’t change with one hemodialysis session we concluded that AT III and D-dimer might be used to observe the activations of coagulation and fibrinolytic system in the patients with CRF on long-term hemodialysis. Işık Türkalp, Aliye Karabulut, Didem Özkazanç. Alterations In Haemostatic Parameters In Patients With Chronic Renal Failure On Regular Hemodialysis Treatment. South Clin Ist Euras. 2003; 14(2): 74-80 Sorumlu Yazar: Işık Türkalp |
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