Online Makale
Online Hizmetlere Toplu BakışTurkish Journal of Hematology
Turk J Hematol. 2008; 25(4): 190-194 | |||
Doğuştan olmayan akut miyeloid lösemiye yönelik ilk gerilemenin kazanılmasında moleküler sitogenetik aberasyonların önemiMilena G. Velizarova1, Evgueniy A. Hadjiev2, Kamelia V. Alexandrova2, Dora N. Popova3, Ivanka Dimova4, Boriana M. Zaharieva4, Draga Toncheva41Department Of Clinical Laboratory And Clinical Immunology, University Alexander’s Hospital, Sofia, Bulgaria2Clinic Of Hematology, University Alexander’s Hospital, Sofia, Bulgaria 3Department Of Blood Transfusion And Immunology, Lab Of Clinical Immunology, Hospital For Emergency Medicine "n. I. Pirogov", Sofia, Bulgaria 4Department Of Medical Genetics, Medical University, Sofia, Bulgaria AMAÇ: Akut miyeloid lösemi (AML) teşhisi konulan yetişkinlerin büyük çoğunluğu edinsel sitogenetik aberasyona sahiptir. Bu makalede AML’ye ilişkin majör sitogenetik bulgular sunulmakta ve ilk tam remisyon üzerindeki klinik anlamları incelenmektedir. Significance of molecular-cytogenetic aberrations for the achievement of first remission in de novo acute myeloid leukemiaMilena G. Velizarova1, Evgueniy A. Hadjiev2, Kamelia V. Alexandrova2, Dora N. Popova3, Ivanka Dimova4, Boriana M. Zaharieva4, Draga Toncheva41Department Of Clinical Laboratory And Clinical Immunology, University Alexander’s Hospital, Sofia, Bulgaria2Clinic Of Hematology, University Alexander’s Hospital, Sofia, Bulgaria 3Department Of Blood Transfusion And Immunology, Lab Of Clinical Immunology, Hospital For Emergency Medicine "n. I. Pirogov", Sofia, Bulgaria 4Department Of Medical Genetics, Medical University, Sofia, Bulgaria OBJECTIVE: The majority of adults diagnosed with acute myeloid leukemia (AML) display acquired cytogenetic aberrations at presentation. In this article, we present the major cytogenetic findings regarding AML and review their clinical significance for achievement of the first complete remission. Milena G. Velizarova, Evgueniy A. Hadjiev, Kamelia V. Alexandrova, Dora N. Popova, Ivanka Dimova, Boriana M. Zaharieva, Draga Toncheva. Significance of molecular-cytogenetic aberrations for the achievement of first remission in de novo acute myeloid leukemia. Turk J Hematol. 2008; 25(4): 190-194 Sorumlu Yazar: Milena G. Velizarova, Bulgaria |
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