Oral Bacteria of Children with Turner Syndrome

INTRODUCTION: Turner syndrome (TS) is a genetic disorder caused by numerical or structural aberration of the X chromosome, which is associated with a female phenotype. Concerning oral status several studies have revealed that girls with TS have dental anomalies and periodontal problem. The aim of the study was to evaluate the effect of oral bacteria on caries prevalence and periodontal status, in pediatric patients with TS.
METHODS: Twenty TS patient and 17 healthy girl were examined for cariological and periodontal status. The levels of mutans streptococci (MS), lactobacilli (LB), yeast and 10 different periodontal bacteria were determined by using culture and microarray techniques in children 's stimulated saliva samples.
RESULTS: There was no difference in salivary flow rate and buffering capacity, DMFT, MS, LB, yeast levels in the groups. PI and GI levels were significantly higher in the Turner group and dft was significantly higher in the control group (p < 0,05). As a result microarray analysis, P. intermedia, F. nucleatum, E. corrodens, A. actinomycetemcomitans, A. viscosus were detected at high levels in Turner group (p < 0,05).
DISCUSSION AND CONCLUSION: Besides dental and craniofacial anomalies, the clinicians should be cautious with in early diagnosis and treatment of periodontal problems in patients with TS.